High-Quality Linaclotide CAS NO: 851199-59-2 Manufacturers, Quotes
Product Description
Mechanism & Efficacy
Linaclotide is a guanylate cyclase-C agonist that enhances intestinal fluid secretion and accelerates transit, commonly used in research on chronic constipation and irritable bowel syndrome with constipation (IBS-C).
Dosage & Research Use
Linaclotide, approved clinically for chronic idiopathic constipation and IBS‑C, typically comes in microgram doses (e.g., 72 mcg, 145 mcg, 290 mcg capsules in clinical settings). Research applications should reflect standard mg‑to‑mcg scaling and follow rigorous protocols. (Note: This product is intended for research and not for direct clinical application.)
Patents & Intellectual Property
Linaclotide’s therapeutic patents (e.g., US 8,703,911 B2) protect the peptide’s structure and use in gastroenterological conditions, with core protections expected to expire from mid‑2020s through early 2030s depending on jurisdiction.
Quality & Compliance
Manufactured in cGMP-compliant facilities, each batch undergoes rigorous testing for purity, stability, and identity, ensuring high-quality research-grade material.
Customer Service & Shipping
Technical support is available for research protocols, peptide handling, and storage guidance.
Products are shipped using specialized temperature-controlled packaging to maintain stability, with monitoring and tracking provided.
Therapeutic Areas
A Solution for IBS-C and Chronic Constipation
One of the highlights of linaclotide is its targeted approach to treating constipation. While over-the-counter laxatives can provide temporary relief, they may lead to dependence or other side effects, while linaclotide addresses the underlying issues associated with irritable bowel syndrome (IBS-C) and chronic constipation (CIC). By enhancing the natural processes of the digestive system, linaclotide helps restore balance and promote a healthier intestinal environment.
Patients using linaclotide reported significant improvements in their symptoms, including increased bowel movement frequency and reduced abdominal discomfort. Many users experienced a new sense of freedom, allowing them to engage in daily activities without the constant worry of constipation. Whether it’s dining out with friends or participating in a sporting activity, linaclotide helps people enjoy life to the fullest.
Outlook & Development
Linaclotide is easy to fit into your daily life. It is usually taken once daily and can be taken with or without food, making it a convenient option for people with busy lifestyles. Your healthcare provider will guide you on the appropriate dose based on your specific needs to ensure you get the best benefit from this medicine.
As with any medication, it is important to discuss your medical history and any potential interactions with your healthcare provider before starting to take linaclotide. While most patients tolerate this medication well, some may experience mild side effects, such as diarrhea or abdominal pain. These side effects are usually temporary and can be managed with the guidance of a healthcare professional.
In summary, linaclotide is a breakthrough treatment option for patients with IBS-C and chronic constipation (CIC). By increasing intestinal fluid secretion and promoting regular bowel movements, linaclotide offers a safe and effective way to relieve constipation symptoms. Don’t let IBS-C or chronic constipation bother you anymore. Talk to your healthcare provider today to learn how linaclotide can help you restore digestive health and improve your overall health. Experience the relief you deserve and take the first step toward a more comfortable, active lifestyle.
